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Intragenic Tsc2 Somatic Mutations as Knudson's Second Hit in Spontaneous and Chemically Induced Renal Carcinomas in the Eker Rat Model |
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| Authors: | Toshiyuki Kobayashi Shinji Urakami Youko Hirayama Toshiki Yamamoto Masae Nishizawa Tomoko Takahara Yoshiaki Kubo Okio Hino |
| Institution: | Department of Experimental Pathology, Cancer Institute, 1–37-1 Kami-Ikebukuro, Toshima-ku, Tokyo 170 |
| Abstract: | |
| Keywords: | Tuberous sclerosis (Tsc2) gene Hereditary cancer Tumor suppressor gene Eker rat Two-hit |