内镜下逆行阑尾炎治疗术治疗急性非穿孔性阑尾炎疗效对比的Meta分析

目的 系统性评价内镜下逆行阑尾炎治疗术(ERAT)治疗急性非穿孔性阑尾炎的安全性和有效性.方法 检索Pubmed、Cochrane图书馆对照试验注册库、中国期刊全文数据库、万方数据库、维普数据库,自2012年1月至2019年4月有关内镜下逆行阑尾炎治疗术和腹腔镜手术治疗急性非穿孔性阑尾炎的相关文献,采用Cochrane...

Meta-analysis of the efficacy comparison of retrograde endoscopic appendicitis in the treatment of acute non-perforated appendicitis

Objective To explore the feasibility of endoscopic retrograde appendicitis in the treatment of acute non-perforated appendicitis.Method Retrieve the pubmed、cochrane Library Control Test Registration Database,Chinese Journal full text Database,Wanfang Database,Weipu Database,from January 2012 to April 2019 related literature on endoscopic retrograde appendicitis and laparoscopic surgery for acute non-perforated appendicitis,the Cochrane collaboration with Rev Man 5.3 edition software for statistical processing,analyze the heterogeneity in data,calculate the OR value OR MD and its 95%confidence interval.Results 16 clinical studies with a total of 1375 patients were enrolled according to the inclusion criteria.Meta analysis showed that endoscopic retrograde appendicitis treatment and laparoscopic surgery for acute non-perforated appendicitis compared the curative effect,endoscopic retrograde appendicitis treatment of shorter hospital stay MD(95%CI)=-2.46(-2.93,-1.99),P<0.05,Lower incidence of complications OR(95%CI)=0.23(0.160.33),P<0.05,Short operation time MD(95%CI)=-19.89(-21.8,-17.93),P<0.05,and Postoperative recovery was faster MD(95%CI)=-3.16(-4.13,-2.19),P<0.05.Conclusions the results of meta-analysis suggest that endoscopic retrograde appendicitis is a safe and feasible method for the treatment of acute non-perforatedre appendicitis,which has many advantages,such as short operation time,short hospitalization time,rapid recovery of patients,fewer complications,and good cosmetic effect,However,at present,this treatment method is not completely popular,and this conclusion needs to be confirmed by large-scale clinical data.