| 隐球菌荚膜抗原检测在隐球菌病中的诊断价值 |
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| 作者姓名： | 陈力 何小庆 陈耀凯 |
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| 作者单位： | 重庆市公共卫生医疗救治中心急诊科;重庆市公共卫生医疗救治中心感染科 |
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| 基金项目： | “十三五”国家科技重大专项(2018ZX10302104);重庆市医学科研重点项目(2019ZDXM012)。 |
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| 摘 要： | 隐球菌病是由隐球菌感染人体引起的一种侵袭性真菌病,是艾滋病患者及实体器官移植者中常见的感染和致死原因.10年来,隐球菌病的诊断方法 已从真菌培养、墨汁染色,到目前的隐球菌荚膜抗原(cryptococcal capsular antigen,CrAg)检测.CrAg检测操作简便快速,花费少,敏感性及特异性高,因此在世界范...
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| 关 键 词： | 隐球菌荚膜抗原 隐球菌病 诊断价值 |
The value of detecting cryptococcal antigen in the diagnosis of cryptococcosis |
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| Authors: | Chen Li He Xiaoqing Chen Yaokai |
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| Institution: | (Department of Emergency,Chongqing Public Health Medical Center,Chongqing 400036,China;Department of Infectious Diseases,Chongqing Public Health Medical Center,Chongqing 400036,China) |
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| Abstract: | Cryptococcosis is an invasive fungal disease caused by cryptococcosis,it is a common cause of infection and death among AIDS patients and solid organ transplant recipients.In the past ten years,the diagnostic methods for cryptococcosis have ranged from fungal culture and ink staining to the current detection of cryptococcal capsular antigen(CrAg).CrAg detection is simple and fast,inexpensive,high sensitivity and specificity,so it is widely used worldwide.The World Health Organization recommends CrAg screening for high-risk groups and preemptive treatment of CrAg-positive patients to reduce the mortality rate.This article reviews the value of cryptococcal capsularantigendetecting in the diagnosis of cryptococcosis. |
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| Keywords: | Cryptococcal capsular antigen Cryptococcosis Diagnosis |
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