姬松茸-灰树花-蛹虫草复合多糖对免疫低下小鼠免疫调节的影响

目的:以姬松茸-灰树花-蛹虫草制成的复合多糖,以免疫抑制小鼠细胞免疫功能为主要指标,探究比较复合多糖与各单一多糖对免疫低下小鼠免疫调节功能影响的差别.方法:通过检测小鼠细胞免疫功能和体液免疫功能,并对相关指标进行检验.结果:复合多糖组小鼠的体质量高于同性别的其他单一多糖组;各多糖组小鼠胸腺系数均有不同程度的升高,其中复...

Effects of compound polysaccharides from Agaricus blazei murrill-Griflola frondosa-Cordyceps militaris on the immunological function in immunosuppressive mice

Objective:To compare the effect of compound polysaccharide and single polysaccharide on the immunoregulation of immunocompromised mice.Methods:the cellular immune function and humoral immune function of mice were tested.Results:the body weight of mice in compound polysaccharide group was higher than that of other single polysaccharide groups of the same sex;the thymus coefficient of mice in each polysaccharide group increased to different degrees,and the effect of compound polysaccharide group was the best;the effect of compound polysaccharide group was better than that of single polysaccharide group in serum IgG,IgA,IgM,SIgA;the effect of compound polysaccharide was better than that of single polysaccharide in blood CD4/CD8,spleen CD4/CD8,and blood CD4-CD8+The results showed that the effect of decreasing was good,the effect of increasing T-lymphocyte proliferation rate of compound polysaccharide group was better than that of single polysaccharide group,and the difference was statistically significant(P<0.05).Conclusion:the compound polysaccharide has a better effect on improving the cellular immunity,humoral immunity and T lymphocyte function of mice,and can significantly improve the immune function of immunosuppressed mice.