420nm强脉冲光结合水光注射治疗中重度痤疮的有效性及对GAGS评分的影响研究

目的 420nm强脉冲光联合水光注射治疗中重度痤疮疗效分析.方法 以随机样本抽样法,在我院收治的94例中重度痤疮患者中随机分为对照组、观察组,各47例,对照组:单纯采用420nm强脉冲光治疗,观察组:应用420nm强脉冲光联合水光注射治疗,对比两组治疗有效率、血清因子水平、皮肤屏障功能及痤疮综合分级系统(GAGS)评分...

Efficacy of 420nm intense pulsed light combined with water-light injection in the treatment of moderate and severe acne and its effect on GAGS score

Objective Efficacy of 420nm intense pulsed light combined with water light injection in the treatment of moderate and severe acne.Method Using random sampling method,94 patients were randomly divided into Control Group(N=47)and Observation Group(N=47),Control Group:420 nm intense pulsed light,observation Group:420nm intense pulsed light combined with waterlight injection was used to compare the effective rate,serum factor level,skin barrier function and GAGS score,and the incidence of complications.Result The effective rate of treatment in the observation group was significantly higher than that in the Control Group(P≪0.05),and the level of serum factor and the score of GAGS in the same group after treatment were significantly lower than those before treatment(P≪0.05),and the degree of decline was more obvious in the Observation Group(P≪0.05).The skin barrier function of the observation group was significantly improved than that of the Control Group(P≪0.05).The incidence of complications(red mark,pigmentation and scar)was significantly lower than that of Control Group(P≪0.05).Conclusion The combination of 420nm intense pulsed light and water-light injection is effective in the treatment of moderate and severe acne.It can reduce inflammation,repair skin barrier and reduce complications.