| 免疫检查点抑制剂相关心肌炎的诊治进展 |
| |
| 引用本文： | 刘杰,张燕军,王云梅,姚俊涛. 免疫检查点抑制剂相关心肌炎的诊治进展[J]. 临床医学研究与实践, 2021, 6(6): 193-195 |
| |
| 作者姓名： | 刘杰 张燕军 王云梅 姚俊涛 |
| |
| 作者单位： | 西安医学院,陕西 西安,710068;西安交通大学医学院附属陕西省肿瘤医院,陕西 西安,710061;西安交通大学医学院附属陕西省肿瘤医院,陕西 西安,710061 |
| |
| 摘 要： | 免疫调节是控制恶性肿瘤进展的重要决定因素,免疫检查点抑制剂(ICIs)的应用为恶性肿瘤治疗带来突破性进展,很大程度上改善了患者的生存时间和生活质量,然而不可避免的是,其也带来免疫相关不良反应(irAE)毒性风险.本文就ICIs相关心肌炎的发病机制、发病率、诊断和治疗策略进行综述.
|
| 关 键 词： | 免疫检查点抑制剂 心肌炎 恶性肿瘤 |
Progress in diagnosis and treatment of immune checkpoint inhibitors-associated myocarditis |
| |
| LIU Jie,ZHANG Yanjun,WANG Yunmei,YAO Juntao. Progress in diagnosis and treatment of immune checkpoint inhibitors-associated myocarditis[J]. Clinical Research and Practice, 2021, 6(6): 193-195 |
| |
| Authors: | LIU Jie ZHANG Yanjun WANG Yunmei YAO Juntao |
| |
| Affiliation: | (Xi'an Medical University,Xi'an 710068;Shaanxi Provincial Cancer Hospital Affiliated to Medical College of Xi'an Jiaotong University,Xi'an 710061,China) |
| |
| Abstract: | Immune regulation is an important determinant for the control of the malignant tumors progression.The application of immune checkpoint inhibitors(ICIs)has brought breakthroughs in the treatment of malignant tumors,and greatly improve the survival time and quality of life of patients.However,it is inevitable that the ICIs also brings the toxicity risk of immune-related adverse events(irAE).This paper reviews the mechanism,incidence,diagnosis and treatment strategies of ICIs-associated myocarditis. |
| |
| Keywords: | immune checkpoint inhibitors myocarditis malignant tumor |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
