创面愈合相关机制的研究进展

创面是一种以皮肤缺损或功能受限为主要特征的常见外科病症.感染、异物、局部血液循环障碍及某些基础疾病等因素不仅会影响创面的愈合,持续发展甚至还会出现全身皮肤感染,代谢紊乱,创周血管硬化,周围神经损伤及肢体功能障碍等一系列并发症.创面愈合问题一直是烧伤整形科面临的最具挑战的问题.本文阐述了国内外对相关炎症因子、生长因子、免...

Research progress on related mechanisms of wound healing

Wound is a common surgical disease characterized by skin defect or functional limitation.Infections,foreign bodies,local blood circulation disturbances and certain underlying diseases will not only affect the healing of wounds,but will also continue to develop and even cause a series of complications like systemic skin infections,metabolic disorders,peri-wound vascular sclerosis,peripheral nerve injury and limb dysfunction.The problem of wound healing has always been the most challenging problems faced by the burns and plastic surgery department.This article describes the research progress on the roles and the mechanisms of related inflammatory factors,growth factors,immune cells and related signal pathways in wound repair at home and abroad,and aims to provide reliable theoretical basis and new ideas for basic and clinical research on promoting wound healing.