| 蛛网膜下腔出血患者血液黏附分子及脑脊液中SOD MDA含量的动态变化研究 |
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| 引用本文： | 陆士奇,程晓娟,杨美菊,余志华,冀勇. 蛛网膜下腔出血患者血液黏附分子及脑脊液中SOD MDA含量的动态变化研究[J]. 中国急救医学, 2007, 27(1): 18-20 |
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| 作者姓名： | 陆士奇 程晓娟 杨美菊 余志华 冀勇 |
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| 作者单位： | 1. 215006,江苏,苏州大学附属第一医院急诊科
2. 250033青岛,山东大学第二医院神经外科 |
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| 摘 要： | 目的研究自发性蛛网膜下腔出血(SAH)患者血液黏附分子及脑脊液中SOD、MDA的动态变化规律。方法对30例SAH患者血清可溶性细胞间黏附分子(sICAM-1)、可溶性血管内皮间黏附分子(sVCAM-1)及脑脊液中SOD、MDA进行动态观察。结果SAH患者血清sICAM-1、sVCAM-1在发病后升高,以发病后5～7 d变化最明显；SOD在早期出现短暂升高后迅速下降,MDA则与之相反。结论SAH患者血液黏附分子及脑脊液中SOD、MDA含量与病情演变有关。
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| 关 键 词： | 蛛网膜下腔出血 可溶性黏附分子-1 超氧化物歧化酶 丙二醛 |
| 文章编号： | 1002-1949(2007)01-0018-03 |
| 修稿时间： | 2006-09-28 |
Dynamic changes of the concentrations of sCAM-1 in serum and SOD, MDA in CSF in the patients with subarachnoid hemorrhage |
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| LU Shi - qi, CHENG Xiao - juan, YANG Mei - ju,et al.. Dynamic changes of the concentrations of sCAM-1 in serum and SOD, MDA in CSF in the patients with subarachnoid hemorrhage[J]. Chinese Journal of Critical Care Medicine, 2007, 27(1): 18-20 |
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| Authors: | LU Shi - qi CHENG Xiao - juan YANG Mei - ju et al. |
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| Affiliation: | Department of Emergency, the First Hospital Affiliated to Sochoow University, Stuzhou 215006, China |
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| Abstract: | Objective To study the dynamic changes of the concentrations of sCAM-1 in serum and SOD,MDA in cerebrospinal fluid(CSF)of the patients with SAH.Methods Dynamic changes of the concentration of sCAM-1 in serum and SOD,MDA in CSF were measured.Results sICAM-1 and sVCAM-1 in serum increased and were the most obvious between 5 days and 7 days.SOD decreased rap- idly after transient increase,the condition of MDA was opposite.Conclusion The changes of illness cor- related with the concentration of sCAM-1 in serum,SOD and MDA in CSF. |
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| Keywords: | Subarachnoid hemorrhage(SAH) Soluble cellular adhesion molecules(sCAM-1) Superoxide dismutase(SOD) Malondialdehyde(MDA) |
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