| 针刺对胰岛素抵抗模型大鼠游离脂肪酸含量的影响 |
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| 引用本文： | 孙健,谢长才,贾真,许能贵,易玮.针刺对胰岛素抵抗模型大鼠游离脂肪酸含量的影响[J].山东中医药大学学报,2009,33(3). |
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| 作者姓名： | 孙健 谢长才 贾真 许能贵 易玮 |
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| 作者单位： | 孙健,谢长才,SUN Jian,XIE Chang-cai(广东省中医院针灸科,广东,广州,510120);贾真,JIA Zhen(广东药学院,中药学院,广东,广州,510006);许能贵,易玮,XU Neng-gui,YI Wei(广州中医药大学针灸推拿学院,广东,广州,510405)
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| 摘 要： | 目的:观察针刺对胰岛素抵抗(IR)模型大鼠血清、心肌、肝脏和骨骼肌游离脂肪酸(FFA)含量的影响。方法:将24只大鼠随机分成空白组、模型组、针刺组,检测比较FBG、INS、ISI及血清、心肌、肝脏和骨骼肌FFA的含量。结果:与空白组比较,模型组大鼠FBG、INS升高,ISI降低(均P<0.01);与模型组比较,针刺组大鼠FBG、INS降低,ISI升高(均P<0.01)。与空白组比较,模型组大鼠血清、心肌、肝脏和骨骼肌内FFA含量显著升高(均P<0.01);与模型组比较,针刺组大鼠血清、心肌、肝脏和骨骼肌FFA含量显著降低(P<0.05或P<0.01)。结论:针刺对胰岛素抵抗有一定的逆转作用,该作用可能是通过减轻IR大鼠血清、心肌、肝脏和骨骼肌内FFA的生成和堆积来实现的。
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| 关 键 词： | 胰岛素抵抗 针灸疗法 游离脂肪酸 模型大鼠 实验研究 |
Effect of acupuncture on free fatty acid content of experimental rats with insulin resistance |
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| SUN Jian,XIE Chang-cai,JIA Zhen,XV Neng-gui,YI Wei.Effect of acupuncture on free fatty acid content of experimental rats with insulin resistance[J].Journal of Shandong University of Traditional Chinese Medicine,2009,33(3). |
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| Authors: | SUN Jian XIE Chang-cai JIA Zhen XV Neng-gui YI Wei |
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| Institution: | 21. Acupuncture and Moxibustion Department;Guangdong Province Hospital of TCM;Guangzhou 510120;China;2. Chinese Materia Medica Faculty;Guangdong Pharmaceutical University Guangzhou 510006;3. Acupuncture and Massage Faculty;Guangzhou University of Traditional Chinese Medicine;Guangzhou 510405;China |
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| Abstract: | Objective:To observe the effect of acupuncture on free fatty acid(FFA) content of correlated tissues for experimental rats with insulin resistance(IR) . Methods:Twenty-four rats were randomly divided into 3 groups:blank group,model group and acupuncture group. Each group had 8 rats. Blank group rats were fed by normal forage,the other two groups rats were induced into insulin resistance models by feeding of high-fat-sugar-salt forage. After models were induced successfully,blank group rats were fed by norma... |
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| Keywords: | insulin resistance acupuncture therapy free fatty acid model rat experimental study |
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