On-site digital quantitative coronary angiography: comparison with visual readings in interventional procedures

In order to review the morphological criterion for an interventional procedure, diameter stenosis (%DS) of 226 coronary lesions in 200 patients undergoing elective coronary angiography with an option for prima vista angioplasty (pPTCA), was assessed on-site by both visual eye balling (EB) and independent digital quantitative coronary angiography (DQCA) by means of an angiographic workstation. Compared to DQCA, EB overestimated the %DS between 50 and 80% and accounted for the majority of discrepancies with overestimation up to 45%. Concordant estimates of %DS by both methods were observed in only 10 of the total of 226 stenotic segments; in 20 of 226 cases, EB underestimated %DS up to 20%. EB revealed a %DS 60% in 166 stenoses (73.4%), an estimate that led to subsequent pPTCA. However, only 119 (52.6%) of these lesions had a %DS 60% as assessed objectively by DQCA. With regard to the criterion for PTCA 47 of 166 performed pPTCA (28.3%) would not meet the indication criteria based on objective DQCA information. EB and DQCA (± 5%DS) had concordant results and criteria for pPTCA only in 103 of 166 coronary lesions (62.1%). These results lead to the conclusion that, on-site and on-line DQCA by an independent cardiologist eliminates both under- and overestimation of stenoses as seen with EB. DQCA supports immediate decision-making and appears necessary for reliable evaluation of coronary morphology in an interventional catheterization laboratory setting and may eventually ensure intraprocedural quality control.