Comorbidities and Health Status in Individuals With and Without COPD in Five Latin American Cities: The PLATINO Study |
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| Authors: | Maria Victorina López Varela María Montes de Oca Ronald Halbert Adriana Muiño Carlos Tálamo Rogelio Pérez-Padilla José Roberto B. Jardim Gonzalo Valdivia Julio Pertuzé Ana María B. Menezes |
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| Affiliation: | 1. Servicio de Neumología, Hospital Maciel, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay;2. Servicio de Neumonología, Hospital Universitario de Caracas, Facultad de Medicina, Universidad Central de Venezuela, Caracas, Venezuela;3. Department of Community Health Sciences, UCLA School of Public Health, Los Angeles, CA, United States;4. Laboratorio de Sueño, Instituto de Enfermedades Respiratorias, Mexico City, Mexico;5. Respiratory Division, Escola Paulista de Medicina, Sâo Paulo, Brazil;6. Departamento de Salud Pública, Facultad de Medicina, Pontifícia Universidad Católica de Chile, Santiago de Chile, Chile;7. Cátedra de Neumología, Facultad de Medicina, Pontifícia Universidad Católica de Chile, Santiago de Chile, Chile;8. Faculdade de Medicina, Universidade Federal de Pelotas, Pelotas, Brazil;1. Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA;2. Partners In Health, Boston, MA 02215, USA;3. The Fenway Institute, Fenway Health, Boston, MA, USA;4. Department of Psychiatry, Harvard Medical School, Boston, MA, USA;1. Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina, USA;2. Department of Medicine, Duke Comprehensive Cancer Center, Duke University Medical Center, Durham, North Carolina, USA;3. Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina, USA;4. Department of Palliative and Supportive Services, Flinders University, Adelaide, South Australia, Australia;5. Department of Medicine, Flinders University, Adelaide, South Australia, Australia;6. Southern Adelaide Palliative Services, Repatriation General Hospital, Daw Park, South Australia, Australia;7. Drug and Therapeutic Information Service, Repatriation General Hospital, Daw Park, South Australia, Australia;8. School of Pharmacy, University of Queensland, Brisbane, Queensland, Australia;9. Western Palliative Care Service, Queen Elizabeth Hospital and Health Service, Woodville, South Australia, Australia;10. Southern Division of General Practice, Bedford Park, South Australia, Australia;11. Department of Biostatistics, School of Nursing, University of South Australia, Adelaide, South Australia, Australia;1. University of California Irvine School of Medicine, Irvine, California;2. Veterans Affairs Long Beach Health Care System, Long Beach, California;1. Indiana University School of Medicine, OrthoIndy Cartilage Restoration Center, Indianapolis, Indiana, U.S.A.;2. Comparative Orthopaedic Laboratory, Columbia, Missouri, U.S.A.;3. Department of Orthopaedic Surgery, Missouri Orthopaedic Institute, University of Missouri, Columbia, Missouri, U.S.A.;1. Servicio de Neumología, Hospital del Mar–IMIM, Barcelona, Spain;2. Departamento de Ciencias Experimentales y de la Salud (CEXS), Universitat Pompeu Fabra, Barcelona, Spain;3. Centro Radiológico Computarizado (CRC), Bunyola (Mallorca), Spain;4. Centro Radiológico Computarizado (CRC), Barcelona, Spain;5. Servicio de Neumología, Fundación Cardiovascular de Colombia, Bucaramanga, Colombia;1. Division of Nephrology, Atlanta VA Medical Center and Emory University, Atlanta, Georgia;2. Division of Nephrology and Hypertension, University of California Medical Center, Orange, California |
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| Abstract: | IntroductionComorbidities are common in patients with chronic obstructive pulmonary disease (COPD), and have a significant impact on health status and prognosis. The PLATINO study provides data on self-reported comorbidities and perceived health status in COPD subjects.MethodsPLATINO is a population-based study on COPD prevalence in five Latin American cities. COPD diagnosis was defined by GOLD criteria (FEV1/FVC<.70 post-bronchodilator). Information was collected on the following comorbidities: heart disease, hypertension, diabetes, cerebrovascular disease, peptic ulcer and asthma. Health status was evaluated using the SF-12 questionnaire, derived from the question: “In general, would you say your health is excellent, very good, good, fair or poor?” A simple comorbidity score was calculated by adding the total number of comorbid conditions.ResultsOf a total population of 5314 individuals, 759 had COPD. Reported comorbidities by decreasing frequency were: any cardiovascular disease, hypertension, peptic ulcer, heart disease, diabetes, cerebrovascular disease, asthma and lung cancer. COPD patients had a higher comorbidity score and prevalence of lung cancer (P<.0001) and asthma (P<.0001), as well as a higher tendency to have hypertension (P=.0652) and cerebrovascular disease (P=.0750). Factors associated with comorbidities were age, body mass index (BMI) and female gender. The number of comorbidities increased as the health status deteriorated.ConclusionsIn the PLATINO population-based study, COPD individuals had an increased number of comorbidities. Age, female gender and higher BMI were the factors associated with comorbidity in these patients. Comorbid conditions were associated with impaired health status, independently of the COPD status. |
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| Keywords: | Epidemiology Comorbidities General health status Chronic obstructive pulmonary disease Epidemiología Comorbilidades Estado general de salud Enfermedad pulmonar obstructiva crónica |
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