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Endometrioid Ovarian Carcinoma During Pregnancy Presenting With Acute Rupture
Authors:Stephanie Gottheil  Jacob McGee
Affiliation:1. Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto ON;2. Division of Obstetrics and Gynaecology, Mount Sinai Hospital, Toronto ON;3. Division of Endocrinology, University of Toronto, Toronto ON;4. Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto ON;5. Department of Nutritional Sciences, University of Toronto, Toronto ON;6. Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto ON;1. Department of Medicine, University of Toronto, Toronto ON;2. Department of Obstetrics and Gynaecology, St. Michael’s Hospital, University of Toronto, Toronto ON;1. National Institute of Public Health of Quebec, Quebec City QC;2. Department of Obstetrics and Gynecology, Laval University, Quebec City QC;3. Department of Agribusiness and Consumer Sciences, Laval University, Quebec City QC;4. Department of Nursing Sciences, Laval University, Quebec City QC;5. National Institute of Graduate Studies and Research in Care, IUFRS, University of Lausanne, Lausanne, Switzerland;1. Department of Obstetrics and Gynaecology, Catharina Hospital, Eindhoven, the Netherlands;2. Department of Obstetrics and Gynaecology, McMaster University, Hamilton ON;3. Department of Midwifery Science VU Medical Center, Amsterdam, the Netherlands;4. Department of Midwifery Science, Zuyd University, Maastricht, the Netherlands;5. Department of Medical Health Psychology, University of Tilburg, Tilburg, the Netherlands
Abstract:BackgroundEndometrioid ovarian carcinoma is rarely diagnosed during pregnancy and is generally asymptomatic. We present a case of endometrioid ovarian carcinoma during pregnancy that presented with acute rupture, and discuss options for management.CaseA primigravid woman presented at 26 weeks’ gestation with severe abdominal pain. At laparotomy, an adnexal mass was found to have ruptured. The mass was identified postoperatively as an endometrioid ovarian carcinoma. The decision was made to perform Caesarean section with fertility-sparing surgical management at 34 weeks to maximize maternal and fetal outcomes.ConclusionTo our knowledge, this is the first reported case of endometrioid ovarian carcinoma presenting with rupture in pregnancy. The differential diagnosis of severe abdominal pain during pregnancy should include rupture of ovarian malignancy.
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