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Characteristics of Asthma Patients Admitted to an Intermediate Respiratory Care Unit
Authors:Belén Núñez  Federico Fiorentino  Ana Kersul  Sonia Belda  Susana García  Catalina Gutiérrez  Ernest Sala  Borja Cosío
Affiliation:1. Department of Clinical Laboratory, Shanghai Pulmonary Hospital affiliated to Tongji University, Shanghai, 200433, PR China;2. Department of Clinical Laboratory, Qingpu Branch of Zhongshan Hospital affiliated to Fudan University, Shanghai, 201700, PR China;3. National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, PR China;1. Department of Pathology, Radboud University Medical Center, P.O. Box 9101, Nijmegen, 6500 HB, The Netherlands;2. Department of Pathology, Canisius Wilhelmina Hospital, P.O. Box 9015, Nijmegen, 6500 GS, The Netherlands;3. Department of Obstetrics and Gynecology, Radboud University Medical Center, P.O. Box 9101, Nijmegen, 6500 HB, The Netherlands;4. Department of Pathology, Leiden University Medical Center, P.O. Box 9600, Leiden, 2300 RC, The Netherlands
Abstract:IntroductionIntermediate respiratory care units (IRCU) provide continuous monitoring and non-invasive mechanical ventilation (NIMV) in patients with severe respiratory failure who are usually admitted to intensive care units (ICUs). The usefulness of IRCU in managing severe asthma exacerbations has never been evaluated.MethodsClinical data were prospectively and systematically compiled from patients admitted to the IRCU with a principal diagnosis of bronchial asthma exacerbation. We assessed therapeutic failure (intubation or exitus) and patient evolution up until 6 months after discharge compared with a group of patients admitted to a conventional hospital ward, paired for age and sex, and with the same principal diagnosis.ResultsA total of 74 asthma patients were included (37 admitted to IRCU and 37 to the hospital ward) with a mean age (±SD) of 58 ± 20, who were predominantly women (67%), with previous diagnosis of asthma and persistent asthma treatment. The main cause of admittance to the IRCU was severe respiratory failure. The patients who were admitted to the IRCU presented more radiological affectation (alveolar infiltrates) and had significantly higher pCO2. Ten patients admitted to the IRCU required non-invasive mechanical ventilation (NIMV). There were no differences between the two groups regarding either therapeutic failure or the 6-month follow-up after discharge.ConclusionsPatients with severe asthma exacerbations can be managed in an IRCU while avoiding hospitalization in an ICU and demonstrating a prognosis similar to milder exacerbations treated in conventional hospital wards.
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