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RNA干扰在眼底疾病中的新进展
引用本文:孟博,雷宁玉. RNA干扰在眼底疾病中的新进展[J]. 国际眼科杂志, 2010, 10(4): 700-702. DOI: 10.3969/j.issn.1672-5123.2010.04.029
作者姓名:孟博  雷宁玉
作者单位:滨州医学院附属医院眼科,中国山东省滨州市,256603
基金项目:中国山东省教育厅立项课题资助项目 
摘    要:RNA干扰(RNAi)发现,改变了人们对细胞基因调控的传统理解。这种技术具有传统治疗方法无可比拟的优势和潜力,因此近些年来越来越受全世界眼科医师的重视。目前,虽然在临床应用中还存在不少问题,但是RNAi必将为眼科疾病的治疗带来新的前景。我们就RNAi在眼底方面的研究进行综述。

关 键 词:RNA干扰  眼底病  基因沉默

Study on RNA interference technology in fundus diseases
Bo Meng and Ning-Yu Lei. Study on RNA interference technology in fundus diseases[J]. International Eye Science, 2010, 10(4): 700-702. DOI: 10.3969/j.issn.1672-5123.2010.04.029
Authors:Bo Meng and Ning-Yu Lei
Affiliation:Department of Ophthalmology, the Affiliated Hospital of Binzhou Medical College, Binzhou 256603, Shandong Province, China;Department of Ophthalmology, the Affiliated Hospital of Binzhou Medical College, Binzhou 256603, Shandong Province, China
Abstract:The discovery of RNA interference(RNAi)has changed people’s traditional concepts of the gene.This technique posseses advantages and potentials that traditional therapies can not compare especially in terms of its specificity and efficiency,and it is drawing more and more attentions from ophthalmologists all over the world these year. Although there are still a lot of problems in clinical use at present,various kinds of related experimental results make us firmly believe that RNAi will surely bring a new epoch for curing diseases in ophthalmology.This article provides an overview on some of the latest advances in fundus.
Keywords:RNA interference  fundus diseases  gene silencing
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