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Characterization of Multidrug-Resistant Group B Streptococci with Reduced Penicillin Susceptibility Forming Small Non-Beta-Hemolytic Colonies on Sheep Blood Agar Plates
Authors:Hirotsugu Banno  Kouji Kimura  Yosuke Tanaka  Hiromitsu Kitanaka  Wanchun Jin  Jun-ichi Wachino  Keiko Yamada  Keigo Shibayama  Yoshichika Arakawa
Institution:aDepartment of Bacteriology, Nagoya University Graduate School of Medicine, Aichi, Japan;bDepartment of Bacteriology II, National Institute of Infectious Diseases, Tokyo, Japan;cDepartment of Microbiology Laboratory, Yokohama City Seibu Hospital, St. Marianna University School of Medicine, Kanagawa, Japan
Abstract:We isolated and characterized three multidrug-resistant clinical isolates of group B streptococci with reduced penicillin susceptibility (PRGBS) that formed small non-beta-hemolytic colonies on sheep blood agar plates but grew well on chocolate agar plates. They can be overlooked in the bacterial identification step, leading to clinical misdiagnosis and treatment failure.
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