Photodynamic Therapy for Bowen's Disease of the Vulva Area |
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Authors: | Hong-Kyu Kang Jeong-Hwan Yun Young-Min Son Joo-Young Roh Jong-Rok Lee |
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Affiliation: | Department of Dermatology, Gachon University Gil Medical Center, Incheon, Korea. |
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Abstract: | Bowen''s disease is a squamous cell carcinoma in situ and has the potential to progress to a squamous cell carcinoma. The authors treated two female patients (a 39-year-old and a 41-year-old) with Bowen''s disease in the vulva area using topical photodynamic therapy (PDT), involving the use of 5-aminolaevulinic acid and a light-emitting diode device. The light was administered at an intensity of 80 mW/cm2 for a dose of 120 J/cm2 biweekly for 6 cycles. The 39-year-old patient showed excellent clinical improvement, but the other patient achieved only a partial response. Even though one patient underwent a total excision 1 year later due to recurrence, both patients were satisfied with the cosmetic outcomes of this therapy and the partial improvement over time. The common side effect of PDT was a stinging sensation. PDT provides a relatively effective and useful alternative treatment for Bowen''s disease in the vulva area. |
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Keywords: | Bowen''s disease Photochemotherapy Vulva area |
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