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Quantitative bone gallium scintigraphy in osteomyelitis
Authors:O A Sorsdahl MD  G L Goodhart MD  H T Williams MD  L J Hanna MD  J Rodriquez MD
Institution:(1) Department of Nuclear Medicine, Georgia Baptist Medical Center, Atlanta, Georgia, USA;(2) Department of Internal Medicine, Divisions of Infectious Disease and Hyperbaric Medicine, Georgia Baptist Medical Center, Atlanta, Georgia, USA;(3) Department of Orthopedic Surgery, Georgia Baptist Medical Center, Atlanta, Georgia, USA;(4) Department of Nuclear Medicine, Georgia Baptist Medical Center, 300 Boulevard, N.E., 30312 Atlanta, GA, USA
Abstract:Gallium imaging offers many practical advantages over indium-111-labeled leukocyte imaging, and calculating quantitative ratios in addition to performing the routine bone-gallium images allows accurate and easy evaluation of patients with suspected osteomyelitis. To add objectivity and improve the accuracy and confidence in diagnosis of osteomyelitis, quantitative comparison of abnormalities seen on bone scans and gallium scans was performed. One hundred and ten adult patients with 126 sites of suspected osteomyelitis were evaluated and categorized by gallium-to-bone ratios, gallium-tobackground ratios, and spatial incongruency of gallium and bone activity. Combined evaluation using these criteria gave a 70% sensitivity and 93% specificity for the diagnosis of osteomyelitis.
Keywords:Bones infection  radionuclide studies-Gallim  radioactive
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