某精神病院住院患者药物使用时点调查

目的了解某精神病院住院患者药物使用状况,提高医院临床合理用药水平。方法利用天津市安宁医院HIS系统对全部住院患者采用一日法进行用药时点调查。结果当日共调查616例患者,其中单用一种抗精神病药有499例(81.0%),联用两种59例(9.6%),联用三种1例(0.2%)。抗精神病药总用药例次为635,其中利培酮使用频度居首位317例(49.9%),其次为氯氮平163例(25.7%),喹硫平40例(6.3%)。共54例(8.8%)患者使用心境稳定剂,使用频率居前三位的分别为丙戊酸镁26例(48.1%),丙戊酸钠19例(35.2%),卡马西平9例(16.7%)。共222例(36.0%)患者使用抗焦虑和镇静催眠药物,其中苯二氮艹卓类药物中使用氯硝西泮74例(33.3%),其次为阿普唑仑61例(27.5%)、艾司唑仑30例(13.5%)。在躯体疾病辅助用药中,心脑血管疾病药、降糖药、保肝药物使用例数分别为468例(76.0%)、123例(20.0%)、73例(11.9%)。结论精神病院住院患者中非典型抗精神病药的使用占主导地位,且符合单一用药原则,药物使用剂量合理,但应控制苯二氮艹卓类药物的使用。

Time point survey of drug use inpatients of psychiatric hospital

Objective To learn the status of drug use of inpatients in psychiatric hospitals,and to improve the level of hospital clinical rational drug use. Methods All hospitalized patients were investigated with a day of drug use point of time survey by the HIS system of Tianjin Anning Hospital. Results A total of 616 patients were investigated at that day. There were 499 cases(81. 0% )of single use of antipsychotic drugs,59 cases(9. 6% )with two kinds of drugs,1 case(0. 2% )with three kinds of drugs. The total cases of antipsychotic drug use were 635. The frequency of use in the first place was risperidone(317 cases,49. 9 % ),the second was 163 cases with clozapine(25. 7 % ),the third was 40 cases with quetiapine(6. 3 % ). A total of 54(8. 8% )patients were treateed with mood stabilizer. That frequency of use were magnesium valprote(26 cases,48. 1% ),sodium valproate(19 cases,35. 2% )and car-bamazepine(9 cases,16. 7% ). A total of 222 patients(36. 0% )were treated with anti anxiety and sedative hypnotic drugs. The most frequently used were clonazepam(74 cases,33. 3% ),alprazolam(61 cases,27. 5% )and estazolam(30 cases,13. 5% ). The use frequency of cardiovascular disease drugs,hypoglycemic agents,hepatoprotective drugs were 468 cases(76. 0% ),123 cases(20. 0% ) and 73 cases(11. 9% )in the auxiliary medicine of the body disease. Conclusion The frequency of use of atypical antipsychotic drugs in mental hospital inpatients is dominant and conformed to the principle of single drug use. Drug use dosage is reasonable. But the use of benzodiazepine(BDZ)should be controlled.