惊恐障碍患者童年期创伤经历与疾病严重程度关系研究

目的研究惊恐障碍患者童年期创伤经历是否与疾病严重程度相关。方法采用儿童期创伤问卷(CTQ)对在四川省人民医院心身医学科住院患者中,符合《精神障碍诊断与统计手册(第4版)》(DSM-IV)惊恐障碍诊断标准的早年(16岁以前)有过负性经历的90名患者进行调查,采用惊恐障碍严重程度量表(PDSS)评估惊恐障碍严重程度,分析童年期创伤经历与疾病严重程度的关系。结果根据CTQ结果,90名惊恐障碍患者中,情感虐待的检出率为64.8%,躯体虐待检出率为40.7%,性虐待检出率为31.9%,情感忽视检出率为89.0%,躯体忽视检出率为91.2%。CTQ总评分(40.65±11.34)分,PDSS评分(12.75±5.61)分,CTQ总评分及各种创伤经历与惊恐严重程度无线性相关。结论惊恐障碍患者童年期创伤经历与惊恐障碍严重程度无线性相关。

Correlation between childhood trauma experience and disease severity in patients with panic disorder

Objective To find out whether the childhood trauma experience is associated with the severity of panic disorder. Methods 90 inpatients diagnosed with panic disorder according to DSM - IV were enrolled in this study. The Childhood Truama Questinnaire(CTQ)was used to investigate their early negative experiences( before 16 years old),and the disease severity was assessment with Panic Disorder Severity Scale(PDSS). Pearson correlation analysis was employed to analyze the correlation between the disease severity and childhood trauma experience. Results According to the result of CTQ,among 90 patients with panic disorder, 64. 8% had emotional abuse experience,physical abuse was 40. 7% ,sexual abuse was 31. 9% ,emotional neglect was 89. 0% ,and the body neglect was 91. 2% . Total CTQ score was(40. 65 ± 11. 34),and PDSS score was(12. 75 ± 5. 61). The correlation between childhood trauma and panic disorder severity was not statistically significant. Conclusion There is no linear correlation between childhood trauma experience and panic disorder severity.