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Cutaneous cytotoxic T-cell lymphoma
Authors:Weinstabl A  Megahed M  Rütten A  Rübben A
Affiliation:1. Klinik f??r Dermatologie und Allergologie, RWTH Aachen University, Pauwelsstra?e 30, 52074, Aachen, Deutschland
2. Dermatopathologie Friedrichshafen, Bodensee, Deutschland
Abstract:Cutaneous cytotoxic T-cell lymphoma is a rare variant of cutaneous T-cell lymphoma, which shows immunoreactivity for CD56+. We report on an 83-year old woman with numerous skin infiltrates and nodules mainly on her face and trunk. Histopathologic criteria lead to the diagnosis of cutaneous cytotoxic T-cell lymphoma. Bexarotene was not tolerated because of cardiac insufficiency, but treatment with methotrexate (7.5 mg once weekly) led to prompt regression of all lesions.
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