Successful use of levosimendan in a patient with peripartum cardiomyopathy |
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Authors: | Benlolo Sidney Lefoll Cécile Katchatouryan Vahan Payen Didier Mebazaa Alexandre |
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Affiliation: | Department of Anesthesiology and Critical Care Medicine, H?pital Lariboisière, Assistance Publique-H?pitaux de Paris, Institut Fédératif de Recherche 06, Paris, France. |
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Abstract: | This case represents the first reported use of levosimendan, a calcium-sensitizing drug with additional vasodilation properties, for treatment of a woman with peripartum cardiomyopathy. Levosimendan induced a steady decline of increased pulmonary capillary wedge pressure, followed by a definitive increase in cardiac stroke volume. The patient recovered from this serious episode of heart failure, and she ultimately regained left ventricular function. IMPLICATIONS: Acute heart failure is a life-threatening event that only rarely occurs during childbirth. We report a case of a woman who experienced cardiovascular collapse during vaginal delivery. We determined that she met current diagnostic criteria for peripartum cardiomyopathy, and we successfully treated her with levosimendan, a calcium-sensitizing drug with additional vasodilation properties. |
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