盆腔静脉瘀血症患者瘀血静脉超微结构观察

为探讨盆腔静脉瘀血症患者瘀血静脉形态学改变,本文对11例瘀血症患者和6例结扎术后无任何症状和体征的妇女盆腔静脉进行了扫描及透射电镜观察.发现瘀血静脉壁间渗出增多;内皮细胞数量增多、体积变小且外形肿胀;细胞表面粗糙,突起增粗,小孔及凹陷增多、变大;细胞质致密并含大量饮液泡,线粒体肿胀而数量增多;染色质呈块状分布于核的周边;内皮细胞间嵌合连接和紧密连接正常存在.这些变化说明缺氧是引起本症盆腔静脉超微结构改变的主要原因,提示本症是一种功能性疾病.

Ultrastructure of Pelvic Congestive Vein of Pelvic Congestion Syndrome after Sterilization

Ultrastructure of congestive veins of 11 cases of pelvic venous congestion syndrome after sterilization (PVCSS) and 6 apparently normal women after sterilization were observed. Results showed :exudate inside congestive venous wall was increased; pelvie congestive venous endothelialcells of PVCSS were swelling. The number of these cells increased but they were smaller in volume. Cellular surface,with more and bigger holes,pittings and protrudings,was rough. Cytoplasm of some cells were dense with granular appearance and many pinosomes were present in endothelial cells. Mitochondria, with cristae becoming shorter and less, were swelling, but increased in number. Chromatin,gathering as block,distributed on the internal surface of nuclear membrane. Mosaic junctions and tight junctions between the pelvic congestive venous endothelial cells were normal. These suggest that anoxia is the main cause of pelvic congestive venous number ultra-structure of PVCSS. Without sign of irreversible pathologic changes,hence PVCSS is a venous functional disease.