| 卵巢恶性肿瘤患者血清和腹腔液唾液酸的动态变化 |
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| 引用本文： | 郝翠芳,王明正.卵巢恶性肿瘤患者血清和腹腔液唾液酸的动态变化[J].滨州医学院学报,1996(4). |
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| 作者姓名： | 郝翠芳 王明正 |
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| 作者单位： | 滨州市附属医院妇产科，西安医科大学第二临床医学院 |
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| 摘 要： | 本文动态检测卵巢恶性肿瘤患者血清及腹腔液总唾液酸（ＴＳＡ）和脂质结合唾液酸（ＬＳＡ）含量，并与正常女性及卵巢良性肿瘤患者比较。结果表明，卵巢恶性肿瘤患者血清及腹腔液ＴＳＡ、ＬＳＡ含量明显高于良性肿瘤及健康对照（Ｐ＜０．０１，Ｐ＜０．００１），且血清及腹腔液ＴＳＡ、ＬＳＡ含量随卵巢恶性肿瘤临床分期的加重而升高（Ｐ＜０．０５，Ｐ＜０．０１），提示动态检测血清和腹腔液ＴＳＡ、ＬＳＡ含量可用于卵巢良、恶性肿瘤的鉴别及早期卵巢癌的诊断，并有助于了解患者的术后病情变化，估计预后，观察疗效，指导临床治疗方案。
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| 关 键 词： | 卵巢肿瘤 唾液酸 动态检测 |
DYNAMIC DETERMINATION OF SIALIC ACID FROM SERUM AND ABDOMINAL CAVITY FLUID OF PATIENTS WITH OVARIAN CANCER |
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| Hao Cuifang,et al.DYNAMIC DETERMINATION OF SIALIC ACID FROM SERUM AND ABDOMINAL CAVITY FLUID OF PATIENTS WITH OVARIAN CANCER[J].Journal of Binzhou Medical College,1996(4). |
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| Authors: | Hao Cuifang |
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| Abstract: | Serum and abdominal cavity fluid levels of total sialic acid(TSA) and lipid bound sialic acid (LSA)were determined in 30 ovarian malignant tumors,30 ovarian benign tumors and 50 normal individuals,respectively.The results showed that:1) Serum and abdominal cavity fluid TSA and LSA levels of malignant ovarian tumors were higher than those of benign ovarian tumors dnd normal controls(P<0.01,P<0.001);2) Serum and abdominal cavity fluid levels of TSA,LSA increased gradually from early to advanced stage of the ovarian malignant tumors(P<0.05,P<0.01).These findings suggested that TSA,LSA may be a useful indicator for diagnosing the malignant tumors and prognosticating the tumors'developments. |
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| Keywords: | ovarian neoplasms sialic acid dynamic determination |
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