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帕金森氏病、帕金森氏综合征、原发性震颤的TGAb、TMAb和甲状腺功能的测试研究
引用本文:许继平,孙丰润,李爱云,范卫明,李风英,刘孟安.帕金森氏病、帕金森氏综合征、原发性震颤的TGAb、TMAb和甲状腺功能的测试研究[J].滨州医学院学报,1993(2).
作者姓名:许继平  孙丰润  李爱云  范卫明  李风英  刘孟安
作者单位:滨州医学院帕金森病研究所 (许继平),滨州医学院附属医院药剂科 (孙丰润),滨州医学院附属医院神经科 (李爱云,范卫明,李风英),滨州医学院附属医院中医科(刘孟安)
摘    要:对78例帕金森氏病、帕金森氏综合征、原发性震颤做了TGAb、TMAb和甲状腺功能的研究,并与正常人和急性脑血管疾病患者做了对照.研究结果显示帕金森氏病患者的TGAb、TMAb阳性率远高于帕金森氏综合征、特发性震颤和两个对照组,尤以震颤少动型为最高.TGAb、TMAb阳性者,其甲状腺功能降低,呈低T_3综合征.作者对这一现象的发生机理与帕金森氏病之间的相互可能关系做了讨论.

关 键 词:帕金森氏病  原发性震颤  抗甲状腺球蛋白抗体  抗甲状腺微粒体抗体

STUDY ON TGAb,TMAb AND THYROID FUNCTION IN PARKINSON'S DISEASE,PARKINSON'S SYNDROME AND ESSENTIAL TREMOR
Xu Jiping,et al.STUDY ON TGAb,TMAb AND THYROID FUNCTION IN PARKINSON''''S DISEASE,PARKINSON''''S SYNDROME AND ESSENTIAL TREMOR[J].Journal of Binzhou Medical College,1993(2).
Authors:Xu Jiping  
Abstract:The serum thyroglubulin antibodies (TGAb), thyroid microsomal antibodies (TMAb)and thyroid function were studied in 78 cases of Parkinson's disease(PD),Parkinson's syndrome (PS) and essential tremor (ET) by radioimmunoassay. At the same time the TGAb, TMAb and thyroid function were compared with those in 30 healthy controls and 30 patients with acute cerebrovascular disease. The results showed that the positive rates of TGAb, TMAb in PD were higher than those in PS,ET and coatrol groups,and highest in the tremor type of patients with PD. The thyroid functions in patients with positive TGAb,TMAb were lower than those in control and negative Ab groups. The lower T_(3) syndrome was present in patients with positive TGAb and TMAb. The possible mechanism and correlation between TGAb,TMAb and PD are discussed.
Keywords:Parkinson's disease  essential tremor  TGAb  TMAb
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