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肌成纤维细胞与心肌梗死后心室重塑
引用本文:高翠菊,高大中. 肌成纤维细胞与心肌梗死后心室重塑[J]. 国际病理科学与临床杂志, 2007, 27(6): 13-524
作者姓名:高翠菊  高大中
作者单位:重庆医科大学附属第二医院心内科,重庆,400010
摘    要:肌成纤维细胞是一组平滑肌样成纤维细胞,在正常心脏仅存在于瓣膜组织中。急性心肌梗死后,来源于成纤维细胞的肌成纤维细胞被激活,是参与心肌梗死后创伤修复与胶原沉积的主要细胞,在心肌间质纤维化和心室重塑中处于中心地位。

关 键 词:肌成纤维细胞  心室重塑  心肌梗死
文章编号:1673-2588(2007)06-0521-04
收稿时间:2007-01-10
修稿时间:2007-01-10

Myofibroblasts and post-infarction ventricular remodeling
GAO Cui-ju,GAO Da-Zhong. Myofibroblasts and post-infarction ventricular remodeling[J]. Journal of International Pathology and Clinical Medicine, 2007, 27(6): 13-524
Authors:GAO Cui-ju  GAO Da-Zhong
Affiliation:Department of Cardiology, Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010,China
Abstract:Myofibroblasts are smooth-muscle-like fibroblasts,and only reside in valve in normal heart.Myofibroblasts which origin from fibroblast are activated after infarction and are major cells in wound recovery and collagen deposition.They also play an important role in interstitial fibrosis and ventricular remodeling.A better knowledge of the characters of myofibroblasts will be conductive to the exploration on new therapies in myocardial interstitial fibrosis.
Keywords:myofibroblasts  ventricular remodeling  myocardial infarction
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