子宫颈电环切除术治疗宫颈上皮内瘤样病变261例报告

目的探讨子宫颈电环切除术(LEEP)治疗宫颈上皮内瘤样病变(CIN)的临床意义。方法回顾性分析2005年6月~2007年6月261例宫颈上皮内瘤样病变患者应用高频电波刀行子宫颈电环切除术(LEEP)的治疗情况。结果治愈率98.47%,术中平均出血量(6.0±0.5)ml,阴道镜下多点活检与子宫颈电环切除术后的病理结果完全符合174例(66.67%),术后降级者66例(25.29%)、升级者21例(8.05%)。术后主要并发症为出血,术后出血大于月经量30例(11.50%)。结论LEEP治疗CIN具有安全、有效、简单易行、并发症少等优点。对防止宫颈癌发生和发展具有重要价值。

REPORT OF CLINICAL ANALYSIS OF 261 CASES OF CERVICAL INTRAEPITHELIAL NEOPLASIA (CIN) TREATED WITH LOOP ELECTROSURGICAL EXCISION PROCEDURE (LEEP)

Objective Examine the clinical significance of Loop Electrosurgical Excision Procedure （LEEP） in the treatment of cervical intraepithelial neoplasia （CIN）. Methods Retrospective analysis of 261 CINcases from June 2005 to June 2007 treated with Loop Eleetrosurgical Excision procedure （LEEP）. Results Cure rate 98.47%, average amount of bleeding in surgery（ 6.0 ± 0. 5 ）ml, multi -points biopsy under vaginoscope perfectly conforming to pathological examination result after conical cervical electro resection in 174 cases （ 66. 67% ） , degrading after the operation in 66 cases （25.29%） , and escalating in 21 cases （8.05%）. Main complication after the operation was bleeding; there were 30 cases （11.50% ） with bleeding quantity larger than menstruation quantity. Conclusion With advantages of safety, validity, east to perform and less complication, LEEP has significant value on prevention of cervical carcinoma from occurrence and development.