| 同型半胱氨酸及其代谢酶基因多态性与动脉粥样硬化和脑梗死 |
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| 引用本文： | 林小慧,李娜,董玉娟.同型半胱氨酸及其代谢酶基因多态性与动脉粥样硬化和脑梗死[J].国际脑血管病杂志,2004,12(5):367-370. |
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| 作者姓名： | 林小慧 李娜 董玉娟 |
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| 作者单位： | 050051,石家庄,河北医科大学第三医院神经内科;050051,石家庄,河北医科大学第三医院神经内科;050051,石家庄,河北医科大学第三医院神经内科 |
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| 摘 要： | 高同型半胱氨酸血症是近年来提出的动脉粥样硬化及其血管并发症新的独立危险因素。造成血浆同型半胱氨酸水平升高的因素主要有营养因素和同型半胱氨酸代谢酶基因多态性 ,后者是否为动脉粥样硬化和脑梗死的基因危险因素目前还存在争论。对高同型半胱氨酸血症的治疗也进行了一些研究。
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| 关 键 词： | 同型半胱氨酸 动脉粥样硬化 脑梗死 基因多态性 |
| 修稿时间： | 2003年11月8日 |
Homocysteine and Its Metabolic Enzyme Polymorphisms Versus Atherosclerosis and Cerebral Infarction |
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| Lin Xiaohui,Li Na,Dong Yujuan.Homocysteine and Its Metabolic Enzyme Polymorphisms Versus Atherosclerosis and Cerebral Infarction[J].International Journal of Cerebrovascular Diseases,2004,12(5):367-370. |
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| Authors: | Lin Xiaohui Li Na Dong Yujuan |
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| Institution: | Lin Xiaohui,Li Na,Dong YujuanDepartment of Neurology,the Third Affiliated Hospital,Hebei Medical University,Shijiazhuang 050051,China |
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| Abstract: | Hyperhomocysteinemia (Hhcy) is a new independent risk factor of atherosclerosis and its vascular complications, which was raised in recent years. The factors that cause the increase of homocysteine levels are primarily nutrition and homocysteine metabolic enzyme polymorphisms. Whether the latter is the gene risk factor of atherosclerosis and cerebral infarction is still controversial. The treatment of Hhcy is also studied. |
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