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血府逐瘀汤对荷瘤小鼠的免疫抑瘤作用
引用本文:刘伯阳,姚淑娟,吕丽艳. 血府逐瘀汤对荷瘤小鼠的免疫抑瘤作用[J]. 中国药业, 2002, 11(10): 44-45
作者姓名:刘伯阳  姚淑娟  吕丽艳
作者单位:黑龙江省齐齐哈尔医学院微生物学教研室,黑龙江,齐齐哈尔,161042
摘    要:目的:研究血府逐瘀汤对荷瘤小鼠的免疫抑瘤作用。方法:以S180荷瘤BALB/C小鼠为模型,系统地研究血夜府逐瘀汤对瘤重和脾细胞免疫功能的影响。结果:血府逐瘀汤灌胃给药8d能显抑制S180瘤重,活化T细胞增殖能力,明显促进自然杀伤细胞(NK)活性和白介素-2(IL-2)分泌水平。结论:血府逐瘀汤抑瘤作用与增强机体细胞免疫功能有关。

关 键 词:荷瘤小鼠 血府逐瘀汤 细胞免疫 白细胞介素-2 肿瘤抑制 作用机制 自然杀伤细胞活性
文章编号:1006-4931(2002)10-0044-02
修稿时间:2001-10-08

The Immunological Tumor- inhibiting Effect of Xuefuzhuyu Soup on Tumor Bearing Mice
Liu Boyang,Yao Shujuan,Lu Liyan. The Immunological Tumor- inhibiting Effect of Xuefuzhuyu Soup on Tumor Bearing Mice[J]. China Pharmaceuticals, 2002, 11(10): 44-45
Authors:Liu Boyang  Yao Shujuan  Lu Liyan
Abstract:Objective:To investigate the immunological tu mor -inhibiting effect of Xuefuzhuyu Soup on tumor bear-ing mice.Methods:S 180 bearing BALB /C mice as model,investigate effects of Xuefuzhuyu Soup on t umor weight and immunological function of splee n cells systematically.Results:8days orally administrated,Xuefuzhuyu Soup can significantly inhibit the tumor weight of S 180 ,activate proliferating ability of T cells,markedly increase activity of natural killers(NK)and secretion of interleukin -2(IL -2).Conclusion:The tumor -inhibiting effects of Xuefuzhuyu Soup relate to reinforcement of cell ular immunity of the body.
Keywords:Xuefuzhuyu Soup  Cellular immunity  Activity of natural killers  Interleukin -2
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