半枝莲的化学成分

目的:对唇形科黄芩属植物半枝莲的化学成分进行研究。方法:采用硅胶柱色谱、Sephadex LH-20柱色谱、重结晶等方法进行分离纯化,根据理化性质和波谱数据鉴定化合物结构。结果:分离鉴定了8个化合物,分别为对羟基苯乙酮(p-hydroxyacetophenone,1),对羟基苯甲醛(p-hydroxybenzaldehyde,2),2-羟基-3-甲基蒽醌(2-hydroxy-3-methylanthraq-uinone,3),香草醛(vanillin,4),5-羟基-7,3’,4’,5’-四甲氧基黄酮(5-hydroxy-7,3’,4’,5’-tetramethoxyflavone,5),5,7-二羟基-6-甲氧基二氢黄酮(dihydrooroxylin A,6),5,7,3’,4’,5’-五甲氧基黄酮(5,7,3’,4’,5’-pentamethoxyflavone,7),金丝桃苷(hyperoside,8)。结论:化合物4,7,8为首次从该属植物中分离得到,化合物6为首次从该种植物中分离得到。

Chemical Constituents of Scutellaria barbata

Objective: To investigate the chemical constituents of Scutellaria barbata. Method: The compounds were isolated and purified by chromatographies on silica gel column and Sephadex LH-20 column together with recrystallization method, and their structures were elucidated on the basis of physical and spectral analyses. Result: Eight compounds were isolated and identified as p-hydroxyacetophenone (1),p-hydroxybenzaldehyde(2), 2-hydroxy-3-methylanthraq-uinone (3), vanillin (4), 5-hydroxy-7, 3', 4', 5'-tetramethoxyflavone (5), dihydrooroxylin A (6), 5, 7, 3', 4', 5'-pentamethoxyflavone (7), hyperoside (8). Conclusion: Compounds 4,7 and 8 were obtained from Scutellaria for the first time. Compound 6 was obtained from the title plant for the first time.