部分脾栓塞治疗门脉高压继发脾功能亢进的疗效观察

目的探讨部分脾栓塞术治疗门脉高压继发脾功能亢进的疗效。方法采用Seldinger法穿刺股动脉，超选择性插管进入脾动脉，行部分性脾栓塞共17例，术前血小板和／或白细胞和／或红细胞计数均明显低于正常水平。结果部分脾栓塞后1～2周血小板、白细胞超过正常范围并达峰值，术后2～3月仍明显高于术前，具有统计学意义（P〈0.05）。红细胞计数变化不明显，无统计学意义（p〉0.05）。17例患者术后均有左上腹疼痛和发热。结论部分脾栓塞术既能有效地缓解脾功能亢进和门脉高压，又能保留脾脏的免疫功能，对门脉高压继发脾功能亢进的患者是一条安全、有效的治疗途径。

The Therapeutic Efficacy of Partial Splenic Arterial Embolization for Hypersplenism Caused by Portal Hypertension

Objective To investigate the therapeutic efficacy of partial splenic arterial embolization for hypersplenism caused by portal hypertension.Methods 17 cases with hypersplenism were treated by partial splenic arterial embolization. The catheters were inserted into the splenic artery selectively through the femoral artery useing Seldinger technique. The platelets （PLT）and/or white blood cells （WBC） and/or red blood cells （RBC） were obviously under normal level before operation.Results The PLT and WBC increased obviously in 1 -2 weeks after operation and returned to normal or exceed it and reached the top, while 2-3 months later they increased obviously than that before operation（p〈0.05）.But the changes of RBC were not obviously（p〉0.05）.The complications included left upper abdominal pain and fever （17 cases）.Conclusion Partial splenic arterial embolization is safe and effective in relieving hypersplenism and portal hypertension.