厦门地区急性呼吸道感染患者肺炎支原体IgM抗体检测分析

目的 分析2012年厦门地区急性呼吸道感染患者肺炎支原体IgM抗体（MP-IgM）检测结果,判断其流行趋势.方法 收集诊断为急性呼吸道感染的患者8 188例,按年龄、性别、季节分组,运用被动凝集法检测血清中MP-IgM,利用统计学软件进行数据处理和分析.结果 急性呼吸道感染患者MP-IgM总阳性检出率为25.1%,女性发病率高于男性（P〈0.01）.1~13岁儿童组MP-IgM阳性率最高,与其他年龄组间比较差异均有统计学意义（P〈0.01）.在冬季MP检出率高,春季检出率低.结论 2012年厦门地区肺炎支原体感染为急性呼吸道感染主要病原体之一,感染率最高的人群为1～13岁的儿童,冬季多发,女性发病率高于男性.

Analysis of IgM to Mycoplasma pneumoniae in patients with acute respiratory infection in Xiamen

Objective To analyze the prevalence of Mycoplasma pneumoniae（MP） through detecting the specific antibodies In patients with acute respiratory infection in Xiamen district in 2012. Methods The serum samples of 8 188 patients with respiratory infection were collected and the levels of MP-IgM were tested by passive particle agglutination method. The samples were divided into different groups based on sex, seasons, and ages, and the positive rate of MP-IgM was statistically analyzed with GrapPad Prism. Results The positive rate of MP-IgM was 25. 1 %（2 059 cases） in 8 188 patients with acute respiratory infection in Xiamen district in 2012. The positive rate was a statistically significant different between males and females, different ages, and different seasons（P〈0.01）. It was showed that more females infected MP than males. The most susceptible group who infected MP was 1 to 13 years old children. There was more patients infected MP in winter than other seasons in 2012. Conclusion MP is one of the main pathogens leading to acute respiratory infection in Xiamen district in 2012. The morbidity of MP is high among the children from 1 to 13 years old. Females show weaker immunity to MP compared to males. People are more susceptible to MP in winter than other seasons.