| 高效液相色谱法测定复方消渴降糖胶囊中槲皮素含量 |
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| 引用本文： | 季波,夏爱军,廖厚知. 高效液相色谱法测定复方消渴降糖胶囊中槲皮素含量[J]. 中国药业, 2013, 22(4): 44-45 |
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| 作者姓名： | 季波 夏爱军 廖厚知 |
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| 作者单位： | 中国人民解放军广州军区广州总医院药剂科;中国人民解放军第303医院药剂科;广西汇科药物研究所 |
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| 摘 要： | 目的建立复方消渴降糖胶囊中槲皮素的含量测定方法。方法采用VP-ODS C18色谱柱（150 mm×4.6 mm,5μm）,以甲醇-0.2%磷酸溶液（50∶50）为流动相,流速为1.0 mL/min,检测波长为360 nm。结果槲皮素进样量在0.202 4～1.012μg范围内与峰面积线性关系良好（r=0.999 9）,平均回收率为100.48%,RSD为1.53%（n=6）。结论所建立的方法准确、灵敏、重现性好,可用于复方消渴降糖胶囊的质量控制。
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| 关 键 词： | 复方消渴降糖胶囊 槲皮素 高效液相色谱法 |
Determination of Quercetin in Compound Xiaoke Sugar-Reducing Capsules |
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| Ji Bo,Xia Aijun,Liao Houzhi. Determination of Quercetin in Compound Xiaoke Sugar-Reducing Capsules[J]. China Pharmaceuticals, 2013, 22(4): 44-45 |
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| Authors: | Ji Bo Xia Aijun Liao Houzhi |
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| Affiliation: | 1.Department of Pharmacy,Guangzhou General Hospital of Guangzhou Military Region,Guangzhou,Guangdong,China 510010; 2.Department of Pharmacy,303 Hospital of PLA,Nanning,Guangxi,China 530021; 3.Guangxi Huike Research Institute of Materia Medica,Nanning,Guangxi,China 530007) |
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| Abstract: | Objective To establish a determination method of the quercetin content in Compound Xiaoke Sugar-Reducing Cap-sules.Methods The VP-ODS C18 column（150 mm×4.6 mm,5 μm） was used with the mobile phase of methanol-0.2% phos-phoric acid solution（50 ∶50）,the flow rate of 1.0 mL/min and the detection wavelength of 360 nm.Results The linear relation of quercetin was good within the range of 0.202 4-1.012 μg（r=0.999 9）.The average recovery rate was 100.48%,RSD 1.53%（n=6）.Conclusion The established method is accurate,sensitive and good in reproducibility,which can be applied to the quality control of Compound Xiaoke Sugar-Reducing Capsules. |
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| Keywords: | Compound Xiaoke Sugar-Reducing Capsules Quercetin HPLC |
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