肠内营养对重型破伤风患者营养支持的探讨

目的 探讨重型破伤风患者应用肠内营养(EN)支持对患者营养状况的影响.方法 将60例重型破伤风患者随机分为EN组和对照组,每组各30例,EN组在常规治疗的基础上给予肠内营养,对照组在常规治疗基础上给予部分静脉营养,于营养支持前一天及营养治疗后第11天检测两组患者的BMI、TSF、MAMC,TP、PA、ALB及Hb等指标,并且全程观察不良反应及疗效.结果 营养支持10天后两组患者的BMI、TSF、MAMC下降不明显,EN组的TP、PA、ALB及Hb均高于同期对照组(P＜0.05).EN组并发症发生率(16.7%)低于对照组(36.7%),两组比较有统计学意义(P＜0.05).结论 早期EN可改善重型破伤风患者蛋白质代谢和患者营养状况,提高了机体免疫功能,减少并发症.

Abstract：

Objective To study the effect of enteral nutrition on patients with severe tetanus. Methods The patients totaled 60 cases were divided into two groups with 30 cases in each. The patients in EN group were treated with enteral nutrition on basis of routine treatment, control group was treated with total parenteral nutrition (TPN). The indicators values of BMI, TSF, MAMC, TP, PAm, m, ALB and Hb were tested on the day before nutrition supports and after nutrition supports 10 days later in two groups. Adverse reaction and the treatment effect were observed simultaneously. Results With nutritional supports 10 days later, two groups had no obvious decline in BMI, TSF and MAMC. TP, PA, ALB and Hb of EN group were higher than those of control group (P＜0.05) . Complication rate of EN group was lower than that of control group, there was significant differences (P＜0.05) . Conclusions Early EN may improve protein metabo lism in patients with severe tetanus and nutritional status.

Study of enteral nutrition on patients with severe tetanus

Objective To study the effect of enteral nutrition on patients with severe tetanus. Methods The patients totaled 60 cases were divided into two groups with 30 cases in each. The patients in EN group were treated with enteral nutrition on basis of routine treatment, control group was treated with total parenteral nutrition (TPN). The indicators values of BMI, TSF, MAMC, TP, PAm, m, ALB and Hb were tested on the day before nutrition supports and after nutrition supports 10 days later in two groups. Adverse reaction and the treatment effect were observed simultaneously. Results With nutritional supports 10 days later, two groups had no obvious decline in BMI, TSF and MAMC. TP, PA, ALB and Hb of EN group were higher than those of control group (P＜0.05) . Complication rate of EN group was lower than that of control group, there was significant differences (P＜0.05) . Conclusions Early EN may improve protein metabo lism in patients with severe tetanus and nutritional status.