| 交感神经兴奋在慢性间歇性低氧引起高血压发生过程中的作用 |
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| 引用本文： | 万南生,陈宝元.交感神经兴奋在慢性间歇性低氧引起高血压发生过程中的作用[J].国际呼吸杂志,2011,31(9):704-707. |
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| 作者姓名： | 万南生 陈宝元 |
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| 作者单位： | 天津医科大学总医院呼吸科,300052 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 交感神经活性增强在阻塞性睡眠呼吸暂停引起的高血压及其他心血管疾病发生过程中起到重要作用.阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)最为明显的特征就是夜间反复的间歇 性低氧,这种间歇性低氧状态对于交感神经激活及血压升高显得尤为重要.以下就OSA相关性间歇性低氧引起的交感神经系统激活以及其...
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| 关 键 词： | 阻塞性睡眠呼吸暂停 高血压 交感神经活性 间歇性低氧 |
Role of sympathetic activation in the pathogenesis of hypertension induced by chronic intermittent hypoxia |
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| WAN Nan-sheng,CHEN Bao-yuan.Role of sympathetic activation in the pathogenesis of hypertension induced by chronic intermittent hypoxia[J].International Journal of Respiration,2011,31(9):704-707. |
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| Authors: | WAN Nan-sheng CHEN Bao-yuan |
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| Abstract: | Increased sympathetic nerve activity play an important role in the pathogenesis of hypertension and other cardiovascular diseases induced by obstructive sleep apnea (OSA). OSA with the most obvious characteristic is the nocturnal repeated intermittent hypoxia, this intermittent hypoxia condition is particularly important in the course of the sympathetic activation and blood pressure increase.A subsequent review in this article will focus on sympathetic nerve activated by intermittent hypoxia of OSA and its relationship to pathogenesis of hypertension. |
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| Keywords: | Obstructive sleep apnea Hypertension Sympathetic nerve activity Intermittent hypoxia |
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