原位肝移植术止凝血变化的初步临床研究

为研究原位移植术中的出血与全身止血凝血改变的关系，本文对一例肝豆核变性患者原位位肝移植手术中凝血，抗凝及纤溶系统的功能进行了系统的观察，在移植主中凝血抗凝系统的功能逐渐降低，在无肝期及重新灌注早期达最低点，随后逐渐恢复，而纤溶系统的功能随手术的进行而逐步增强，在无肝期及重新灌注期达最高峰。

Preliminary clinical study on hemostatic variations in orthotopic liver transplantation

This study is to investigate the relationship between general hemostatic changes and bleeding symptom in orthotopic liver transplantation (OLT). The coagulant,anticoagulant and fibrinolytic function were as-sessed systematically in one case of Wilson's disease undertaking OLT. The coagulant and anticoagulant function reduce gradually in the course of OLT,reaching the lowest in the liver-depleted phase and the early reinfusion phase,then recover afterwards. However, the fibrinolytic function increases gradually during op-eration,reaching the highest in the liver-depleted phase and the reinfusion phase. The cause of bleeding in OLT is multi-factored and the hemostatic function varies characteristically according to the different stage of the OLT.