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糖尿病患者干眼症的临床研究
引用本文:付智勇,王艳玲,王薇. 糖尿病患者干眼症的临床研究[J]. 临床和实验医学杂志, 2010, 9(17): 1285-1287
作者姓名:付智勇  王艳玲  王薇
作者单位:首都医科大学附属北京友谊医院眼科,北京,100050
摘    要:目的探讨糖尿病患者干眼症的临床特点及其相关影响因素。方法对60例糖尿病患者分别测定泪液分泌试验(SIt)、泪膜破裂时间(BUT)及角膜荧光素染色(FL),将各项指标分别与对照组进行对比;并根据病程、糖化血红蛋白(HbA1 c)水平、糖尿病视网膜病变程度将糖尿病患者进行分组,分析各项检查指标与糖尿病病程、血糖控制情况及视网膜病变程度的关系。结果糖尿病组与对照组在干眼症状发生率、泪液分泌试验、泪膜破裂时间及角膜荧光素染色等方面均有显著性差异(χ^2=4.361,P=0.027;t=-3.665,P=0.000;t=-4.028,P=0.000;χ^2=12.912,P=0.001);各项检查指标与患者糖尿病病程及血糖控制情况无明显相关性(r1=-0.076,-0.090,0.051,P〉0.05;r2=-0.063,-0.045,0.037,P〉0.05);与患者糖尿病视网膜病变的程度有明显相关性(r=-0.914,-0.939,0.785,P〈0.01)。结论糖尿病患者干眼症的发生率与糖尿病视网膜病变的程度呈正相关关系。

关 键 词:糖尿病  干眼症  糖尿病视网膜病变

Clinical study on dry eye symptoms in patients with diabetes mellitus
FU Zhi-yong,WANG Yan-ling,WANG Wei. Clinical study on dry eye symptoms in patients with diabetes mellitus[J]. Journal of Clinical and Experimental Medicine, 2010, 9(17): 1285-1287
Authors:FU Zhi-yong  WANG Yan-ling  WANG Wei
Affiliation:FU Zhi-yong,WANG Yan-ling,WANG Wei.Department of Ophthalmology,Beijing Friendship Hospital,Capital University of Medical Sciences,Beijing 100050,China.
Abstract:Objective To evaluate the character of dry eye symptoms in patients with DM and associated factors.Methods Schirmer I test(SIt),tear film break up time(BUT),corneal fluorescein staining(FL) were measured in 60 patients with DM and 60 control subjects,the values were compared between the two groups;60 patients with DM were divided into groups according to the duration of DM,level of HbA1c and the stage of diabetic retinopathy(DR),the dependability of various values between groups were analyzed.Results The di...
Keywords:Diabetes mellitus  Dry eye symptoms  Diabetic retinopathy  
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