Renal insufficiency and vascular complications after primary angioplasty via femoral route. Impact of vascular closure devices use |
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Authors: | Prada-Delgado Oscar Estévez-Loureiro Rodrigo Calviño-Santos Ramón Barge-Caballero Eduardo Salgado-Fernández Jorge Piñón-Esteban Pablo Vázquez-Rodríguez José Manuel Aldama-López Guillermo Flores-Ríos Xacobe Soler-Martín María Rita Vázquez-González Nicolás Castro-Beiras Alfonso |
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Institution: | Servicio de Cardiología, Complejo Hospitalario Universitario de A Coruña, A Coruña, España |
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Abstract: | Introduction and objectivesWe sought to determine the incidence of vascular complications in patients with chronic kidney disease undergoing primary angioplasty via the femoral route; we also evaluated the safety and efficacy of the use of vascular closure devices in this setting.MethodsRegistry of 527 patients undergoing primary angioplasty via the femoral route from January 2003 to December 2008. Chronic kidney disease was defined as creatinine clearance less than 60 mL/min. The primary endpoint was the presence of major vascular complications.ResultsBaseline chronic kidney disease was observed in 166 (31.5%) patients. Patients with chronic kidney disease experienced higher rates of major vascular complications compared to those without worsening of renal function (8.4% vs 4.2%; P=.045), especially those requiring transfusion (6.6% vs 1.9%; P=.006). Among patients with chronic kidney disease, 129 (77.7%) received a vascular closure device and manual compression was used in 37 patients (22.3%). The risk of major vascular complications was significantly lower with vascular closure device use compared to manual compression (4.7% vs 21.6%; P=.003). Multivariable logistic regression analysis showed that the use of a vascular closure device was independently associated with a decreased risk of major vascular complications in patients with chronic kidney disease undergoing primary angioplasty (odds ratio=0.11; 95% confidence interval, 0.03-0.41; P=.001).ConclusionsPatients with chronic kidney disease undergoing primary angioplasty via the femoral route experience higher rates of major vascular complications. The use of vascular closure devices in this group of patients is safe and is associated with lower rates of major vascular complications compared to manual compression.Full English text available from:www.revespcardiol.org |
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Keywords: | AP angioplastia primaria CVM complicaciones vasculares mayores DCV dispositivos de cierre vascular ICP intervencionismo coronario percutáneo IRC insuficiencia renal crónica SCACEST síndrome coronario agudo con elevación del segmento ST |
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