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Brain changes in geriatric depression |
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| Authors: | George S. Alexopoulos Barnett S. Meyers Robert C. Young Robert C. Abrams Charles A. Shamolan |
| Affiliation: | 1. Associate Professor of Clinical Psychiatry, The New York Hospital-Cornell Medical Center, Westchester Division, 21 Bloomingdale Road, White Plains, New York 10605, USA;2. Assistant Professor of Psychiatry, The New York Hospital-Cornell Medical Center, Westchester Division, 21 Bloomingdale Road, White Plains, New York 10605, USA;3. Professor of Clinical Psychiatry, The New York Hospital-Cornell Medical Center, Westchester Division, 21 Bloomingdale Road, White Plains, New York 10605, USA |
| Abstract: | The clinical and neurobiological literature of geriatric depression which focuses on the relationship between depression and dementia is reviewed. The hypothesis that depression of late life and dementia are linked by a spectrum of underlying ageing-associated brain changes is presented, and the implications for future research are discussed. |
| Keywords: | Depression old age cerebral organic factors |