Intravenous infusion of propofol for induction and maintenance of anaesthesia during endoscopic carbon dioxide laser ENT procedures with high frequency jet ventilation |
| |
Authors: | A. Mayne MD K. Joucken MD E. Collard MD DA P. Randour MD |
| |
Affiliation: | 1. Anaesthetist, Department of Anaesthesiology, University Clinics of Mont Godinne, UCL, B-5180, Yvoir, Belgium.;2. Head of Department, Department of Anaesthesiology, University Clinics of Mont Godinne, UCL, B-5180, Yvoir, Belgium. |
| |
Abstract: | Fourteen patients of ASA grades 1 3 were anaesthetised with continuous infusions of propofol and alfentanil for endoscopic carbon dioxide laser ENT microsurgery. Their lungs were ventilated with an oxygen-air mixture using a high frequency jet ventilator. Propofol was given at an initial rate of 120 μg/kg/minute for 10 minutes after a bolus dose of 2.6 mg/kg, and then at 80 fig μg/kg/minute. Alfentanil was given at a rate of 0.5 μg/kg/minute. Arterial pressure decreased significantly after the bolus dose. It increased significantly for a few minutes after laryngoscopy and returned to baseline values during maintenance of anaesthesia. Heart rate increased significantly during induction and until laryngoscopy was performed but it decreased below its initial value after 5 minutes of maintenance. Platelet count and the degree of aggregation did not change during infusion of propofol. |
| |
Keywords: | Anaesthetics, intravenous propofol Ventilation high frequency jet |
|
|