Chemical constituents of Rhamnus procumbens and pharmacological actions of emodin |
| |
| Authors: | S. P. D. Dwivedi V. B. Pandey A. H. Shah Y. B. Rao |
| |
| Affiliation: | 1. Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India;2. College of Pharmacy, King Saud University, Riyadh-11451, Saudi Arabia;3. Department of Pharmacology, Osmania Medical College, Hyderabad, India |
| |
| Abstract: | Musizin, physcon, emodin and frangulin-A have been isolated from the whole plant of Rhamnus procumbens and their structures established by a detailed study of spectral data and also by degradation methods. Pharmacological investigations on emodin have indicated that it possesses intestinal and cardiac stimulant, CNS depressant and analgesic activities. Such activities have not earlier been reported for emodin. This is also the first report of the isolation of these chemical constituents in Rhamnus procumbensf and the second natural occurrence of musizin. |
| |
| Keywords: | Rhamnus procumbens phenolic components pharmacology |
|
|
