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Growth Factors in Nutritional Support |
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| Authors: | Jimmi Hatton Pharm.D. Mark S. Luer Pharm.D. Robert P. Rapp Pharm.D. |
| Affiliation: | 1. Department of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, Kentucky.;2. Department of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, Kentucky. Department of Pharmacy, Albert B. Chandler Medical Center, Lexington, Kentucky. |
| Abstract: | Protein catabolism occurs in the severely stressed patient despite adequate protein supplementation. Supplementation of endogenous growth factors is one mechanism being evaluated to promote anabolism and improve nitrogen retention. Recombinant technology has provided a means to reproduce these endogenous growth factors. Both recombinant human growth hormone (rGH) and recombinant human insulin-like growth factor-1 (rhIGf-1) are undergoing clinical trials to establish their roles in nutritional support. |
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