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An update on the biochemistry of 5-fluorouracil

Authors:	B Ardalan R Glazer

Institution:	2. Division of Medical Oncology, USC Comprehensive Cancer Center, Los Angeles, California 90033, U.S.A.;3. Laboratory of Medicinal Chemistry and Biology, National Cancer Institute, Bethesda, Maryland 25050, U.S.A.

Abstract:

Keywords:	5-FU 5-fluorouracil 5-FUR 5-fluorouridine 5-FUdR 5-fluorodexoyuridine 5-FUMP 5-fluorouridine 5′-monophosphate 5-FUDP 5-fluorouridine 5′-diphosphate 5-FUTP 5-fluorouridine 5′-triphosphate 5-FdUMP 5-fluorodeoxyuridine 5′-monophosphate 5-FdUDP 5-fluorodeoxyuridine 5′-diphosphate 5-FdUTP 5-fluorodeoxyuridine 5′-triphosphate PRPP 5-phosphoribosyl-1-pyrophosphate 5-BrUdR 5-bromodeoxyuridine 5-ClUdR 5-chlorodeoxyuridine ATP adenosine 5′-triphosphate dATP deoxyadenosine 5′-triphosphate 5-FdCTP 5-fluorodeoxycytidine 5′-triphosphate dUMP deoxyuridine 5′-monophosphate TdR deoxythymidine dTMP deoxythymidine 5′-monophosphate dTTP deoxythymidine 5′-triphosphate R-1-P ribose-1-phosphate R-5-P ribose-5-phosphate dR-1-P deoxyribose-1-phosphate poly(A) polyadenylic acid
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