腔内介入治疗在下肢动脉硬化闭塞症中的应用

目的评价腔内介入治疗在下肢动脉硬化闭塞症中的应用价值。方法回顾性分析本院2006年3月至2009年9月腔内介入治疗的90例下肢动脉硬化闭塞症患者的临床资料,并随访其疗效。结果全组手术成功率94.4%(85/90),与治疗前比较,踝/肱指数平均升高0.22±0.15,差异有统计学意义(P0.05)。随访时间3～36个月,随访率96.7%(87/90),术后3、6、12、30月分别有1例、2例、6例、4例复发,其中10例行二次介入手术后好转;3例行截肢/足手术,其中膝上截肢1例,膝下截肢1例,跖骨截除1例。随访期截肢率3.3%(3/90),死亡率为3.3%(3/90)。结论腔内治疗下肢动脉硬化闭塞症创伤小、恢复快,可重复操作,近期疗效满意,远期疗效尚待进一步观察。

Endovascular treatment in lower extremities arteriosclerosis disease (LEAD)

Objective To assess the value of endovascular intervention in treating patients with lower extremity arteriosclerotic occlusive disease. Methods Ninty patients who underwent the interventional treatments from March 2006 to September 2009 were analyzed retrospectively. Results The total technical success rate was 94.4%（85/90）. Compared with the treatment before, average ankle brachial index （ABI） elevation was 0.22 ± 0. 15（P〈0.05）. Eighty-seven patients （96.7%） were followed up from 3 months to 36 months postoperatively. One patients, 2 patients,6 patients, 4 patients were respectively recurrent in 3, 6, 12, 30 months. Ten patients were improved after second interventional treatment, 1 patients with a major amputation, 1 patients with a minor amputation, 1 patients with metatarsal surgical amputation. Amputation rate during follow-up period was 3.3% （3/90）, mortality was 3.3% （3/90）. Conclusion The endovascular treatment of lower extremity arteriosclerotic occlusive disease is safe, effective, mini-invasive, and repetitive, but its long-term investigation is needed.