A novel norovirus recombinant strain GII.4/GII.21 in Bangladesh, 2011 |
| |
Authors: | Shamsun Nahar Mokibul Hassan Afrad Tazin Fahmi Sayra Moni Warda Haque Sumon Kumar Das Abu Syed Golam Faruque Mohammad Sahabuddin Kabir Choudhuri Tasnim Azim Mustafizur Rahman |
| |
Affiliation: | 1. Department of Microbiology, Jahangirnagar University, Savar, Dhaka, Bangladesh 2. Virology Laboratory, icddr,b, 68, Shahid Tajuddin Ahmed Sharani, Mohakhali, Dhaka, 1212, Bangladesh 3. Department of Pharmacy, Jahangirnagar University, Savar, Dhaka, Bangladesh
|
| |
Abstract: | We identified a novel inter-genotype recombinant norovirus strain, Dhaka85/2011/BGD, collected from a stool specimen of a nine-month-old infant who was hospitalized with diarrhea. Molecular investigation and phylogenetic analysis classified its RNA polymerase gene as GII.4-like, which commonly circulates in humans. The capsid gene was classified as GII.21-like, most likely originated from water. The discovery of this novel strain is an illustration of the enormous diversity among the norovirus strains, especially in developing countries and has important implications for future vaccine strategies. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|