多脑叶离断治疗顽固性癫痫

目的 分析多脑叶离断手术治疗顽固性癫痫的预后及神经功能障碍.方法 回顾性分析本院收治的8例多脑叶离断病人临床资料,所有患者均为广泛半球病变,且保留一定的肢体感觉运动等中央区功能,手术方式均为保留中央区的多脑叶离断.随访内容包括发作症状,术后肢体肌力肌张力.结果 至随访结束,按Engel分级：Ⅰ级4例,Ⅱ级3例,Ⅲ级l例.肢体功能障碍轻微.结论 多脑叶离断手术可很好的控制半球病变引起的顽固性癫痫发作,是不适合半球切除或功能半球切除术病例的一个不错选择.

Hemisphericdisconnection for intracable epilepsy

Objective To explore the seizure outcomes and neurological deficits on hemisphericdisconnectiontreatment for intractable epilepsy caused by hemispheric lesions. Methods The clinical data of 8 patients with refractory epilepsy treated with multi-lobe disconnection of the cerebral hemisphere were analyzed retrospectively. Data collection included seizure outcomes and neurological deficits. Seizure frequency was determined using the modified classification of Engel. Results At the end of follow-up, 4 patients achieved Engel class 1,3 were Engel class II. One was Engel 61ass III. There were slightly neurological deficits. Conclusions The multi-lobe disconnection of the cerebral hemisphere can effectively treat the patients with refractory epilepsy caused by severe hemispheric lesions. This operation is particularly indicated to the patients with hemispheric lesion, but without the deficits of the motor, sensory and language functions of the hemisphere.