ⅢB型前列腺炎对精液参数的影响

目的:探讨非炎症性慢性骨盆疼痛综合征(CAPⅢB)对精液参数的影响。方法:检测74例CAPⅢB患者及46例正常男性的精液参数,以美国国立卫生研究院前列腺炎症状评分(NIHCPSI)评估患者症状情况。比较CAPⅢB患者与对照组的精液参数的差别,分析CAPⅢB患者慢性骨盆疼痛症状程度及持续时间与精液主要参数的关系。结果:CAPⅢB患者精液参数中的精液量、液化时间及精子活动力与对照组相比,差异有显著性(P值分别为0.008、0.007及0.001),而精液pH值、精子密度、精子活率和精子畸形百分率两组间相比,差异无显著性(P>0.05)。CAPⅢB患者CPSI评分与精液量、液化时间及精子活动力间无显著相关性(P>0.05),慢性骨盆疼痛症状持续时间与液化时间有显著正相关性(r=0.283,P=0.015),慢性骨盆疼痛症状持续时间与精子活动力呈显著负相关(r=-0.296,P=0.011)。结论:CAPⅢB患者精液量增加,液化时间延长,精子活动力下降;而症状轻重程度与精液量、液化时间及精子活动力无关。

Seminal Parameter Analysis in Noninflammatory Chronic Prostatitis/Chronic Pelvic Pain Syndrome

OBJECTIVE: To investigate seminal parameters in noninflammatory chronic prostatitis/chronic pelvic pain syndrome (CAP III B). METHODS: A total of 74 consecutive cases of patients who had been diagnosed as CAP III B and 46 cases of controls were included in the study. Severity of symptoms in men with CAP III B was defined according to the NIH Chronic Prostatitis Symptom Index (NIH-CPSI). All of them underwent a 'four glass-test' including leukocyte determination in expressed prostatic secretions (EPS), voided urine after prostatic massage (VB3) and ejaculate semen followed by analysis according to WHO. The analysis included seminal volume, pH, duration of liquefaction, sperm density, vitality, motility(a + b) and morphology. Correlations between the duration or the severity of symptoms and spermiogram results in patients with CAP III B were assessed respectively. RESULTS: The CAP III B group and the control group differed significantly in ejaculate volume, duration of liquefaction and motility, while the remaining parameters did not differ significantly. The duration of chronic pelvic pain showed apparently positive correlationship with liquefaction time, while the symptom duration negatively correlated with sperm motility. The NIH-CPSI score had no significant relationship with seminal volume, duration of liquefaction and sperm motility. CONCLUSION: Our results indicate that CAP III B can have a significant negative impact on sperm volume, liquefaction and motility. Our data also supports the results that the longer the duration of symptoms, the more influences on semen liquefaction and motility might be.