Effect of dexamethasone on the expression of binding sites for high-density lipoproteins in cultured rat hepatocytes (Independence of the hormone effect on the intracellular cholesterol pool) |
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| Authors: | Wei Huang T. G. Vishnyakova A. V. Bocharov E. V. Zaitseva E. G. Frolova D. D. Sviridov V. S. Repin J. -L. Nano P. Rompal |
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| Affiliation: | (1) Institute of Experimental Cardiology, Cardiological Research Center, Russian Academy of Medical Sciences, Moscow;(2) Laboratory of Gastroenterology, Nice University, France |
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| Abstract: | It is shown that glucocorticoids play a key regulatory role directed toward the maintenance of an optimal level of binding and internalization of HDL3 in hepatocytes. Their stimulatory effect on the expression of HDL receptors proves to be independent of changes in the CH content in parenchymal cells. Translated fromByulleten' Eksperimentalnoi Biologii i Meditsiny, Vol. 117, N o 1, pp. 50–53, January, 1994 |
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| Keywords: | high-density lipoproteins hormone regulation glucocorticoids dexamethasone hepatocyte culture adrenal-ectomized rats |
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