早期肠内营养对预防重型颅脑损伤应激性溃疡的效果研究

目的 探讨早期胃肠内营养对重型颅脑损伤患者应激性溃疡的影响.方法 选择重型颅脑损伤患者134例,随机分为2组,早期肠内营养组(EEN组)69例在入院或术后24 h内插管鼻饲进食,延迟肠内营养组(DEN组)65例在术后24 h后插管鼻饲进食.比较2组患者发生上消化道出血情况.结果 EEN组上消化道出血率明显低于DEN组.结论 重型颅脑损伤患者尽早实施胃肠内营养,可以减轻应激性溃疡的发生,预防上消化道出血.

Clinical study of early enteral nutrition on prevention of stress ulcer in patients with severe craniocerebral brain injury

Objective To study the effect of early enteral nutrition on stress ulcer in patients with severe craniocerebral injury.Methods 134 patients with severe craniocerebral injury were randomly divided into two groups,the early enteral nutrition group (the EEN group,69 cases) was given nasogastric intubation feeding after hospitalization or within 24 hours postoperation,the delayed enteral nutrition group (the DEN group,65 cases) was given nasogastric intubation feeding 24 hours postoperation.The incidence of upper gastrointestinal bleeding in two groups were compared.Results The incidence of upper gastrointestinal bleeding in the EEN group was significantly lower than that of the DEN group.Conclusions Patients with severe brain injury should be given enteral nutrition as soon as possible to reduce the occurrence of stress ulcer and prevent upper gastrointestinal bleeding.