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慢性肾脏病患者肾功能与微炎症及氧化应激的相关性
引用本文:王荣珍,梁昭红,刘天喜. 慢性肾脏病患者肾功能与微炎症及氧化应激的相关性[J]. 兰州大学学报(医学版), 2011, 37(1): 62-66
作者姓名:王荣珍  梁昭红  刘天喜
作者单位:兰州大学第一医院,肾内科,甘肃,兰州,730000
基金项目:甘肃省科技支撑计划项目
摘    要:目的 探讨慢性肾脏病非透析患者血清中微炎症及氧化应激相关指标的变化及对肾功能的影响.方法 肾功能不同阶段的慢性肾脏病非透析患者84例,分别于入选初,6、12月后测定肾功能、高敏C反应蛋白、白介素-6、丙二醛、血浆谷胱甘肽过氧化物酶,根据其血肌酐增长程度分为4组,并比较其微炎症及氧化应激指标的变化.结果 慢性肾功能不全患...

关 键 词:慢性肾脏病  肾功能  微炎症  氧化应激

Correlation between renal function of chronic kidney disease patients and micro-inflammation and oxidative stress
WANG Rong-zhen,LIANG Zhao-hong,LIU Tian-xi. Correlation between renal function of chronic kidney disease patients and micro-inflammation and oxidative stress[J]. Journal of Lanzhou University (Medical Sciences), 2011, 37(1): 62-66
Authors:WANG Rong-zhen  LIANG Zhao-hong  LIU Tian-xi
Affiliation:WANG Rong-zhen,LIANG Zhao-hong,LIU Tian-xi (Department of Nephrology,First Hospital of Lanzhou University,Lanzhou 730000,China)
Abstract:Objective To investigate the changes of serum micro-inflammation and oxidative stress related-factors in non-dialysis patients with chronic kidney disease and its effects on renal function of these patients.Methods 84 chronic kidney disease non-dialysis patients at different stages of renal insufficiency were chosen.The serum high-sensitivity C-reactive protein, interleukin-6,maleic dialdehyde,glutathione peroxidase and renal function were measured in these patients at the beginning,6 months later and 12 mo...
Keywords:chronic kidney disease  renal function  micro-inflammation  oxidative stress  
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