持续不卧床腹膜透析患者肺动脉高压与超敏C反应蛋白的相关性分析

目的 研究持续不卧床腹膜透析(CAPE)患者中肺动脉高压的患病率,并探讨其肺动脉高压与超敏C反应蛋白水平的相关性.方法 回顾性分析在我院腹透门诊随诊的透析时间超过6个月的CAPD患者,排除有慢性阻塞性肺疾病,严重心脏瓣膜疾病、有肺栓塞病史、左室射血分数小于50%等的CAPE)患者96例,分别记录患者年龄、性别、体重、透...

Relationship between pulmonary hypertension and high-sensitivity C reactive protein in peritoneal dialysis patients

Objective To investigate the relationship between pulmonary hypertension and high-sensitivity C reactive protein(CRP)in patients on continuous ambulatory peritoneal dialysis(CAPD).Method The study was performed in 96 patients undergoing CAPD more than 6 months.Patients that had chronic obstructive pulmonary disease,severe mitral or aortic valve disease,connetive tissure disease,history of pulmonary embolism,left ventricular ejecion fraction<50% were excluded.The information of age,sex,height,weight,time on CAPD and sitting blood pressure was collected.CRP was mesured.All patients were examined using echocardiography.PAH was defined as systolic pulmonary artery pressure(PAP)>35mmHg at rest.Results PAH was detected 21(21.9%) of the 96 CAPD patients.Mean systolic PAP was significantly higher in patients with PAH than in those without PAH(43.0±9.13vs18.22±5.24,P<0.05).The CRP levels were correlated with PAP in CAPD patients(r=0.38,P=0.036).Conclusion PAH is a frequent cardiovascular complication in CAPD pateints.Therefore,continuous systemic inflammation may be enhanced to development of PAH in CAPD patients.